Integrated Solutions from Research to Commercialisation.
Almac is a financially secure, privately owned organisation with over 3,300 employees located within the US and UK. Over 600 companies worldwide, including all the market leaders, use our services, testament itself to the quality, innovation and efficiency of our business as proven over the past 30+ years.
Our vast range of services include:
Biomarker Discovery & Development: Pre-clinical biomarker discovery, through to full companion diagnostic development and clinical test delivery from our CLIA laboratory.
API Services & Chemical Development: Services for all stages of drug development for small molecules, potent and cytotoxic compounds and peptides.
Pharmaceutical Development: Developing clinical candidates into an optimum formulation and manufacturing drug product for all phases of clinical trial supply.
Analytical Services: Delivering comprehensive solutions supporting drug substance and product development programmes.
Clinical Trial Supply: Offering over 20 years experience in clinical supply, packaging, distribution and management.
Clinical Technologies: Providing interactive voice and web response technologies, flexible solutions for patient enrollment, electronic PROs and adaptive trials.
Commercial Services: Services for all drug products from manufacturing, testing and packaging to end-user distribution.
Almac – Partnering to Advance Human Health™
Mr Gildas Lavenant
Mr Philip Diamond
Mr Philip Berry
Mr Glyn Allsop
Mr Simon LawrenceGalen Ltd
Dr Rob GrundyAlmac Discovery
Eden Biodesign is an integrated biopharmaceutical development organisation and part of Watson Pharmaceuticals, Inc. (www.watson.com). Eden Biodesign is designated as Watson’s Centre of Excellence for Biologics, delivering process and product development; cGMP manufacturing and quality/regulatory expertise from a custom-designed facility located in Liverpool, UK.
Mr Kassim Kolia
Fusion Antibodies is a world leader CMO in Antibody Sequencing; Antibody Engineering & Humanization and Expression and Purification of Pre-Clinical Grade Therapeutic & Diagnostic grade Proteins and cGMP scale up.
Dr Paul Kerr
Mr Helmut Elstner
Innova Biosciences Ltds core business is bioconjugation (antibody labeling) the joining of two molecules to form a hybrid conjugate™. Conjugates are used in hospital and research labs around the world; they also feature in consumer items such as pregnancy test kits (the conjugate is responsible for the blue line). Innova™s one-step conjugation method (Lightning-Link) massively simplifies the production of conjugates that are needed for research and immunodiagnostic applications. Innova also offers exclusive services for optimizing the performance of conjugates and developing more sensitive immunodiagnostic tests. Innova also sells several niche products to pharmaceutical research and development labs.
Mr Tom Speedy
NextPharma Technologies is a world class outsourcing partner to the pharmaceutical and biotechnology industries.
We offer a full range of services from early phase product development, through clinical trial packaging (Phases I through III) to high volume commercial manufacturing of New Chemical Entities (NCEs) and generic products. NextPharma is a world leader in pellet technologies and in specialist product manufacturing including hormones, penicillins, cephalosporins and controlled drugs. We are experts in paediatric drug formulation, development and manufacture. In addition to these specialist areas we have capabilities in solids, semi-solids, liquids, sprays and dry dosage form technologies.
NextPharma offers ‘one-stop’ logistics solutions tailored to meet the needs of the global pharmaceutical industry under the rigid standards of cGSP/GDP regulations.
NextPharma operates globally with six product development centres, six manufacturing plants and seven temperature controlled storage and distribution sites across Europe and North America, supplying customers in North America, Europe and Japan. We employ 1,000 people dedicated to serving over 200 customers world wide and a customer base, which includes many of the world’s leading pharmaceutical, specialty pharma and biotechnology companies.
All of our sites are either FDA inspected, in the process of upgrade for inspection or targeted for upgrade for inspection.
Mr Andrew LewinVice President Business Development Europe PDS
Mr David Sykes
Oxford Expression Technologies
OET Ltd is a biotechnology company and centre of excellence for baculovirus based recombinant protein expression. OET provides protein expression products, services, consultancy and training to pharmaceutical and biotech companies and academic institutions. OET is also carrying out an extensive R&D programme.
Dr Richard BroadheadSales & Marketing Manager
Penn services include: CMC Consultancy, Formulation Development, Analytical Development, Clinical Trial Supply, Contract Manufacturing, Qualified Persons Release Services, Paediatrics Formulation and Manufacturing, Hi-Potency capabilities, Orphan drug expertise, More than 30 Years of specials, manufacturing expertise, Comparator Sourcing.
The above offerings are all under one roof providing a strong and easy communication channel between departments making developments, manufacturing and analytical processes.
Mr Michael Kruidenier
Mr David Spillett
Q Chip is using a novel approach to encapsulate therapeutic peptides in bioresorbable polymer microspheres for injection and sustained drug release (SR). We avoid the use of harsh solvents, high temperatures and shearing forces and achieve high API loading and microsphere monodispersity- two of the most important desirable features of any encapsulation approach, minimising production cost and enhancing syringe-ability, with controllable burst release. We have recently demonstrated successful sustained release over one month of octreotide, in a preclinical model. A small initial burst release was seen, followed by sustained and essentially zero order octreotide release over at least 35 days. Interestingly, there was no lag phase of octreotide release which might otherwise mandate additional daily injections to achieve therapeutic dosing.
We have had similar success with one and three month SR formulations of leuprolide and intend to go next to POC in man. Our octreotide and leuprolide SR formulations are available for licensing.
We use a similar benign approach to therapeutic protein encapsulation and are collaborating with Artes GmbH on the encapsulation of interferon alpha 2a for SR - targeting an improvement on the weekly shots of pegylated interferon currently taken by hep C sufferers.
Q Chip is developing novel technology platforms for the encapsulation of therapeutic peptides for sustained release (SR) and is committed to demonstrating its platforms' capabilities by producing POC data on SR depot formulations of two market leading therapeutic peptides, leuprolide and octreotide. These depot products will compete in the oncology market and in Q Chip's view represent de-risked opportunities for potential partners since both should be amenable to abbreviated regulatory procedures. We are willing to consider licensing our leuprolide and octreotide formulations and we are also interested in talking to potential partners with peptides in development - there is a clear opportunity to develop new sustained release formulations that may extend product patent life as well as enhancing patient compliance.
Dr Cora GriffinBusiness Development Manager
Sera Laboratories International
Sera Laboratories International Ltd (Seralab) is an independent UK company providing a fast, friendly and efficient service with a focus on quality and traceability.
Seralab is a leading supplier of control matrices and disease state material from both human and animal models. The company offers the most complete range of human and animal-based research Bioproducts in Europe. Sera Lab provides serum, plasma, whole blood, tissues, microsomes, S9 fractions and fluids from the human model and an extensive range of animal species.
Our product range also includes Cell Culture sera and reagents including FBS, Cell Specific media selected growth factors and a range of standardised reagents and tools for all areas of Stem Cell research.
The Seralab technical and managerial team have, over 20 years, established an unrivalled reputation of working closely with our customers to develop individual, tailor made solutions; often through the development of new products and techniques.
Our commitment to traditional values of quality product, competitive pricing and absolute customer care are assured through our adherence to the spirit and application of ISO9001 accreditation, which we achieved in 2010. We constantly strive for service excellence providing reliability, full traceability and extensive quality control through customer led evolution and innovation.
Ms Jenny MurrayManaging Director
Ms Rosie Davies
Founded in 1976, Simbec Research is one of Europe's premier niche contract research organisations specialising in increasingly complex early clinical studies for the international pharmaceutical and biopharmaceutical industries.
Simbec is one of Europe's foremost CROs with over 35 years' experience in clinical drug development specialising in healthy volunteer and patient volunteer studies (Phase I-IIa). Simbec is a part of the Altasciences Group which means that as well as having laboratories in South Wales, United Kingdom, it also has facilities in Quebec, Canada. Combined facilities offer over 300 beds and an extensive volunteer and patient database.
Simbec have GCP, GLP, GMP and CPA Accreditation. We also have Standard and Supplementary MHRA Accreditation, meaning that as an Investigator Centre we are able to carry out clinical trials with compounds at all levels of risk, including those that require review by an Expert Advisory Group (EAG).
Simbec Clinical Pharmacology Unit (CPU) has extensive experience in conducting and managing safety, tolerability and pharmacokinetic studies, New Chemical Entity (NCE), First into Man, Proof of Concept, radiolabelled, bioavailability and bioequivalence studies, single and multi dose and short and long term studies.